Product Name: FTO Antibody [AG103]
Species Reactivity: Human
Tested Applications: ELISA, IHC, IP, WB
Applications: ELISA: (direct and indirect: 1:2,000-1:5,000). Immunoprecipitation: (5ug/ml per sample in a final reaction volume of 500-1,000ul). Immunohistochemistry: (5-10ug/ml: paraffin sections). Western Blot: (1:2,000-1:5,000 using ECL. Suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Recombinant human FTO.
Host Species: Mouse
Purification:
Physical State: Liquid
CAS NO.: 1434048-34-6
product targets : Rhinovirus (HRV) inhibitors
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 1 mg/ml
Storage Conditions: Stable for at least 1 year after receipt when stored at -20˚C.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Fat Mass and Obesity-associated Protein; FATSO
Accession NO.: NP_036066.2
Protein Ino: 166851822
Official Symbol: Fto
Geneid: 79068
Background: FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
PubMed ID:http://aac.asm.org/content/41/8/1830.abstract
