anti-prdx6 mouse mab

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Recombinant Anti-PRDX6 Mouse mAb Clone Number: JMMR-2488 Host: Mouse Clonality: Recombinant Monoclonal Applications： WB Reactivity: Human, Rat Synonyms: Peroxiredoxin-6, 1-Cys PRX, aiPLA2, LPCAT-5, NSGPx Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2a/kappa Conjugate Unconjugated Synonyms Peroxiredoxin-6, 1-Cys PRX, aiPLA2, LPCAT-5, NSGPx UniProt ID P30041 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Human, Rat Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background PRDX6 is a unique member of the PRDX family, exhibiting both glutathione peroxidase and phospholipase A2 activities. PRDX6 regulates phospholipid turnover in addition to protecting cells against oxidative injury. PRDX6 is expressed in all major organs, with a particularly high level in lung, where it regulates lung surfactant phospholipid synthesis and turnover. Research studies have shown that PRDX6 is aberrantly expressed in various cancers, and can promote cancer cell metastasis and invasion. Elevated expression of PRDX6 and related PRDX family members has also been shown to contribute to drug resistance in cancer cells. PRDX6 is also expressed in neutrophils, where it has been shown to activate NADPH oxidase (NOX2). Cellular location Cytoplasm, Lysosome Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Mouse IgG H&L pAb (HRP Conjugate) Lysate: 1: HeLa, 2: HEK-293, 3: Rat liver Protein loading quantity: 20 μg Exposure time: 30 secondsPredicted band size: 25 kDa Observed band size: 25 kDa :
Recombinant Anti-PRDX6 Mouse mAb Clone Number: JMMR-2488 Host: Mouse Clonality: Recombinant Monoclonal Applications： WB Reactivity: Human, Rat Synonyms: Peroxiredoxin-6, 1-Cys PRX, aiPLA2, LPCAT-5, NSGPx Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2a/kappa Conjugate Unconjugated Synonyms Peroxiredoxin-6, 1-Cys PRX, aiPLA2, LPCAT-5, NSGPx UniProt ID P30041 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:500 – 1:1000 Human, Rat Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background PRDX6 is a unique member of the PRDX family, exhibiting both glutathione peroxidase and phospholipase A2 activities. PRDX6 regulates phospholipid turnover in addition to protecting cells against oxidative injury. PRDX6 is expressed in all major organs, with a particularly high level in lung, where it regulates lung surfactant phospholipid synthesis and turnover. Research studies have shown that PRDX6 is aberrantly expressed in various cancers, and can promote cancer cell metastasis and invasion. Elevated expression of PRDX6 and related PRDX family members has also been shown to contribute to drug resistance in cancer cells. PRDX6 is also expressed in neutrophils, where it has been shown to activate NADPH oxidase (NOX2). Cellular location Cytoplasm, Lysosome Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Mouse IgG H&L pAb (HRP Conjugate) Lysate: 1: HeLa, 2: HEK-293, 3: Rat liver Protein loading quantity: 20 μg Exposure time: 30 secondsPredicted band size: 25 kDa Observed band size: 25 kDa