anti-cxcr4 mouse mab

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Recombinant Anti-CXCR4 Mouse mAb Clone Number: 11541 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: CXC-R4, FB22, Fusin, HM89, LCR1, LESTR, LAP-3, NPYRL, SDF-1 receptor, CD184 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2b/kappa Conjugate Unconjugated Synonyms CXC-R4, FB22, Fusin, HM89, LCR1, LESTR, LAP-3, NPYRL, SDF-1 receptor, CD184 UniProt ID P61073 Immunogen MW (kDa) 43 Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background C-X-C chemokine receptor type 4 (CXCR-4), also known as CD184, is a protein that in humans is encoded by the CXCR4 gene. The protein is a CXC chemokine receptor. CXCR-4 is an alpha-chemokine receptor specific for stromal-derived_x0002_factor-1, a molecule endowed with potent chemotactic activity for lymphocytes. CXCR4 is one of several chemokine co-receptors that HIV can use to infect CD4+ T cells. HIV isolates that use CXCR4 are traditionally known as T-cell tropic isolates. CXCR4 is present in newly generated neurons during embryogenesis and adult life where it plays a role in neuronal guidance. The levels of the receptor decrease as neurons mature. CXCR4 gene mutant mice have aberrant neuronal distribution. This has been implicated in disorders such as epilepsy. Cellular location Membrane, Lysosome, Cell junction Images FC Cell line: JurkatFixative: UnfixedPermeabilization: NonePrimary Ab dilution: 1:100Secondary Ab: Goat Anti-Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies (Black line).Isotype control: Mouse monoclonal IgG2b(Blue line).Description: Line red is the positive signal for :
Recombinant Anti-CXCR4 Mouse mAb Clone Number: 11541 Host: Mouse Clonality: Recombinant Monoclonal Applications： FC Reactivity: Human Synonyms: CXC-R4, FB22, Fusin, HM89, LCR1, LESTR, LAP-3, NPYRL, SDF-1 receptor, CD184 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG2b/kappa Conjugate Unconjugated Synonyms CXC-R4, FB22, Fusin, HM89, LCR1, LESTR, LAP-3, NPYRL, SDF-1 receptor, CD184 UniProt ID P61073 Immunogen MW (kDa) 43 Specificity Product Usage Information Applications Dilution Recommended Species FC 1:50 – 1:100 Human Properties Purity Protein G purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background C-X-C chemokine receptor type 4 (CXCR-4), also known as CD184, is a protein that in humans is encoded by the CXCR4 gene. The protein is a CXC chemokine receptor. CXCR-4 is an alpha-chemokine receptor specific for stromal-derived_x0002_factor-1, a molecule endowed with potent chemotactic activity for lymphocytes. CXCR4 is one of several chemokine co-receptors that HIV can use to infect CD4+ T cells. HIV isolates that use CXCR4 are traditionally known as T-cell tropic isolates. CXCR4 is present in newly generated neurons during embryogenesis and adult life where it plays a role in neuronal guidance. The levels of the receptor decrease as neurons mature. CXCR4 gene mutant mice have aberrant neuronal distribution. This has been implicated in disorders such as epilepsy. Cellular location Membrane, Lysosome, Cell junction Images FC Cell line: JurkatFixative: UnfixedPermeabilization: NonePrimary Ab dilution: 1:100Secondary Ab: Goat Anti-Mouse IgGUnlabeled control: Cells without incubation with primary and secondary antibodies (Black line).Isotype control: Mouse monoclonal IgG2b(Blue line).Description: Line red is the positive signal for