anti-pi3 kinase p85 alpha rabbit mab

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Recombinant Rabbit Monoclonal Anti-PI3 Kinase p85 alpha Rabbit mAb Clone Number: JRMR-110(2) Host: Rabbit Clonality: Recombinant Monoclonal Applications： IHC-P ICC/IF Reactivity: Human, Mouse Synonyms: PIK3R1, GRB1 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms PIK3R1, GRB1 UniProt ID P27986 Immunogen Recombinant human PI3 Kinase p85 alpha fragment MW (kDa) / Specificity Anti-PI3 Kinase p85 alpha Rabbit mAb recognizes endogeneous level of PI3 Kinase p85 alpha protein. Product Usage Information Applications Dilution Recommended Species IHC-P 1:50 – 1:100 Human ICC/IF 1:50 Human, Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement. Cellular location Cytosol, Membrane Images IHC-P Tissue: Human bladder cancerSection type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use)Counter stain: Hematoxylin (Blue)Description: The brown color represents the positive signal observed with :
Recombinant Rabbit Monoclonal Anti-PI3 Kinase p85 alpha Rabbit mAb Clone Number: JRMR-110(2) Host: Rabbit Clonality: Recombinant Monoclonal Applications： IHC-P ICC/IF Reactivity: Human, Mouse Synonyms: PIK3R1, GRB1 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms PIK3R1, GRB1 UniProt ID P27986 Immunogen Recombinant human PI3 Kinase p85 alpha fragment MW (kDa) / Specificity Anti-PI3 Kinase p85 alpha Rabbit mAb recognizes endogeneous level of PI3 Kinase p85 alpha protein. Product Usage Information Applications Dilution Recommended Species IHC-P 1:50 – 1:100 Human ICC/IF 1:50 Human, Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement. Cellular location Cytosol, Membrane Images IHC-P Tissue: Human bladder cancerSection type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use)Counter stain: Hematoxylin (Blue)Description: The brown color represents the positive signal observed with