Product Name :
anti-pdk1 rabbit mab
Isotype :
IgG
Conjugate :
Unconjugated
Synonyms:
PDH kinase 1, PDHK1,
UniProt ID :
Q15118
Immunogen:
Recombinant human PDK1 fragment
MW (kDa) :
/
Specificity:
Anti-PDK1 Rabbit mAb recognizes endogeneous level of PDK1 protein.
Purity :
Protein A purified
Purity :
PBS, Glycerol, BSA
Storage :
Store at -20°C. Avoid freeze/thaw cycles.
Stability:
Stable for 12 months from date of receipt/reconstitution.
Background :
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress. Cellular location Mitochondrion
Images :
IHC-P Tissue: Human liver cancerSection type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100 Primary Ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Description: The brown color represents the positive signal observed with
Vapor Pressure :
Recombinant Rabbit Monoclonal Anti-PDK1 Rabbit mAb Clone Number: JRMR-249 Host: Rabbit Clonality: Recombinant Monoclonal Applications： IHC-P ICC/IF Reactivity: Human, Mouse Synonyms: PDH kinase 1, PDHK1, Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms PDH kinase 1, PDHK1, UniProt ID Q15118 Immunogen Recombinant human PDK1 fragment MW (kDa) / Specificity Anti-PDK1 Rabbit mAb recognizes endogeneous level of PDK1 protein. Product Usage Information Applications Dilution Recommended Species IHC-P 1:100 Human ICC/IF 1:50 Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress. Cellular location Mitochondrion Images IHC-P Tissue: Human liver cancerSection type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100 Primary Ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Description: The brown color represents the positive signal observed with
Recombinant Rabbit Monoclonal Anti-PDK1 Rabbit mAb Clone Number: JRMR-249 Host: Rabbit Clonality: Recombinant Monoclonal Applications： IHC-P ICC/IF Reactivity: Human, Mouse Synonyms: PDH kinase 1, PDHK1, Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms PDH kinase 1, PDHK1, UniProt ID Q15118 Immunogen Recombinant human PDK1 fragment MW (kDa) / Specificity Anti-PDK1 Rabbit mAb recognizes endogeneous level of PDK1 protein. Product Usage Information Applications Dilution Recommended Species IHC-P 1:100 Human ICC/IF 1:50 Mouse Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress. Cellular location Mitochondrion Images IHC-P Tissue: Human liver cancerSection type: Formalin fixed & Paraffin -embedded section Retrieval method: High temperature and high pressureRetrieval buffer: Tris/EDTA buffer, pH 9.0 Primary Ab dilution: 1:100 Primary Ab incubation condition: 1 hour at room temperature Counter stain: Hematoxylin Description: The brown color represents the positive signal observed with
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