Product Name :
anti-sox17 rabbit mab
Isotype :
IgG
Conjugate :
Unconjugated
Synonyms:
SOX-17
UniProt ID :
Q9H6I2
Immunogen:
MW (kDa) :
Specificity:
Purity :
Protein A purified
Purity :
PBS, Glycerol, BSA
Storage :
Store at -20°C. Avoid freeze/thaw cycles.
Stability:
Stable for 12 months from date of receipt/reconstitution.
Background :
SRY-related high mobility group box (SOX) proteins comprise a large family of widely conserved transcription factors. SOX proteins do not directly mediate transcription, but require binding partners that regulate their ability to mediate transcription of target genes that control cell fate determination and development .Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Sox17 negatively regulates oligodendrocyte precursor differentiation by antagonizing β-catenin signaling. Mutation in the corresponding Sox17 gene in humans is associated with a form of vesicoureteral reflux, a disorder characterized by congenital kidney and urinary tract defects Cellular location Nucleus
Images :
WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgGH&L (HRP Conjugate) Lysate: 1: HeLa (Low expression) , 2: SK-OV-3Protein loading quantity: 20 μg Exposure time: 60 secondsPredicted band size: 55 kDa Observed band size: 55 kDa IHC-P Tissue: Human seminoma Section type: Formalin-fixed & Paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH9.0 Primary Ab dilution: 1:200 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use) Counter stain: Hematoxylin (Blue) Description: The brown color represents the positive signal observed with
Vapor Pressure :
Recombinant Rabbit Monoclonal Anti-SOX17 Rabbit mAb Clone Number: JRMR-10804-168B Host: Rabbit Clonality: Recombinant Monoclonal Applications: WB IHC-P Reactivity: Human Synonyms: SOX-17 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms SOX-17 UniProt ID Q9H6I2 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:1000 – 1:2000 Human IHC-P 1:100 – 1:200 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background SRY-related high mobility group box (SOX) proteins comprise a large family of widely conserved transcription factors. SOX proteins do not directly mediate transcription, but require binding partners that regulate their ability to mediate transcription of target genes that control cell fate determination and development .Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Sox17 negatively regulates oligodendrocyte precursor differentiation by antagonizing β-catenin signaling. Mutation in the corresponding Sox17 gene in humans is associated with a form of vesicoureteral reflux, a disorder characterized by congenital kidney and urinary tract defects Cellular location Nucleus Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgGH&L (HRP Conjugate) Lysate: 1: HeLa (Low expression) , 2: SK-OV-3Protein loading quantity: 20 μg Exposure time: 60 secondsPredicted band size: 55 kDa Observed band size: 55 kDa IHC-P Tissue: Human seminoma Section type: Formalin-fixed & Paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH9.0 Primary Ab dilution: 1:200 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use) Counter stain: Hematoxylin (Blue) Description: The brown color represents the positive signal observed with
Recombinant Rabbit Monoclonal Anti-SOX17 Rabbit mAb Clone Number: JRMR-10804-168B Host: Rabbit Clonality: Recombinant Monoclonal Applications: WB IHC-P Reactivity: Human Synonyms: SOX-17 Product Size 100 μl ADD TO CART BUY NOW Quantity Shipping: Ambient temperature Order online or send purchase order to [email protected] FAQ Technical Support Protocols General Information Product Usage Information Properties Target Information Images Recommended Products References BUY NOW General Information Isotype IgG Conjugate Unconjugated Synonyms SOX-17 UniProt ID Q9H6I2 Immunogen MW (kDa) Specificity Product Usage Information Applications Dilution Recommended Species WB 1:1000 – 1:2000 Human IHC-P 1:100 – 1:200 Human Properties Purity Protein A purified Constituents PBS, Glycerol, BSA Storage Store at -20°C. Avoid freeze/thaw cycles. Stability Stable for 12 months from date of receipt/reconstitution. Target Information Background SRY-related high mobility group box (SOX) proteins comprise a large family of widely conserved transcription factors. SOX proteins do not directly mediate transcription, but require binding partners that regulate their ability to mediate transcription of target genes that control cell fate determination and development .Transcription factor Sox17 is a Sox family protein with an established role in endoderm specification during development. In addition, Sox17 plays essential roles in the maintenance of the hematopoietic stem cell pool and for vascular morphogenesis during development. Sox17 negatively regulates oligodendrocyte precursor differentiation by antagonizing β-catenin signaling. Mutation in the corresponding Sox17 gene in humans is associated with a form of vesicoureteral reflux, a disorder characterized by congenital kidney and urinary tract defects Cellular location Nucleus Images WB Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgGH&L (HRP Conjugate) Lysate: 1: HeLa (Low expression) , 2: SK-OV-3Protein loading quantity: 20 μg Exposure time: 60 secondsPredicted band size: 55 kDa Observed band size: 55 kDa IHC-P Tissue: Human seminoma Section type: Formalin-fixed & Paraffin-embedded section Retrieval method: High temperature and high pressure Retrieval buffer: Tris/EDTA buffer, pH9.0 Primary Ab dilution: 1:200 Primary Ab incubation condition: 1 hour at room temperature Secondary Ab: Anti-Rabbit and Mouse Polymer HRP (Ready to Use) Counter stain: Hematoxylin (Blue) Description: The brown color represents the positive signal observed with
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