Product Name: DDX41 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: DDX41 antibody can be used for detection of DDX41 by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 68 kDa Observed: 70 kDa
Immunogen: DDX41 antibody was raised against a 17 amino acid peptide near the amino terminus of human DDX41.The immunogen is located within amino acids 230 – 280 of DDX41.
Host Species: Rabbit
Purification: DDX41 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 6902-77-8
Product: Genipin
Buffer: DDX41 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: DDX41 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DDX41 Antibody: ABS, ABS, Probable ATP-dependent RNA helicase DDX41, DEAD box protein 41
Accession NO.: NP_057306
Protein Ino: 21071032
Official Symbol: DDX41
Geneid: 51428
Background: DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.
PubMed ID:http://aac.asm.org/content/38/5/997.abstract
