Product Name: Connexin 37 Antibody
Species Reactivity: Mouse
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 37 kDa
Immunogen: This Connexin 37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-333 amino acids from the C-terminal region of human Connexin 37.
Host Species: Rabbit
Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
Physical State: Liquid
CAS NO.: 71183-66-9
Product: DL-threo-2-methylisocitrate
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 1.15 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Gap junction alpha-4 protein, Connexin-37, Cx37, GJA4
Accession NO.: P35212
Protein Ino: 8928555
Official Symbol: GJA4
Geneid: 2701
Background: Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.
PubMed ID:http://aac.asm.org/content/36/11/2512.abstract
