Product Name: CSFR (phospho Tyr561) Antibody
Species Reactivity: Human, Mouse
Tested Applications: IHC, WB
Applications: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
User Note:
Predicted Molecular Weight: 130 kDa
Immunogen: CSFR (phospho Tyr561) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 561 (N-S-Y (p)-T-F) derived from Human CSFR .
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 1227633-49-9
Product: StemRegenin 1
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CD115, CSF-1-R, CSFMR, FMS, M-CSFR
Accession NO.: NP_001275634.1
Protein Ino: 27262659
Official Symbol: CSF1R
Geneid: 1436
Background: Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.
PubMed ID:http://aac.asm.org/content/37/5/950.abstract
