Product Name: CMPK2 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, WB
Applications: CMPK2 antibody can be used for detection of CMPK2 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 49 kDa
Immunogen: CMPK2 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human CMPK2.The immunogen is located within amino acids 370 – 420 of CMPK2.
Host Species: Rabbit
Purification: CMPK2 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 188062-50-2
Product: Abacavir (sulfate)
Buffer: CMPK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CMPK2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CMPK2 Antibody: TYKi, TMPK2, UMP-CMPK2, UMP-CMP kinase 2, mitochondrial, Nucleoside-diphosphate kinase
Accession NO.: NP_997198
Protein Ino: 117606370
Official Symbol: CMPK2
Geneid: 129607
Background: CMPK2 Antibody: UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response
PubMed ID:http://aac.asm.org/content/36/8/1738.abstract
