Product Name: CK1 Antibody [3C10F7 / 3C10G5 / PMC01 / 4D12B3]
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: Western Blot:1:500 – 1:2,000 IHC(P):1:500 – 1:2,000IHC(F):1:500 – 1:2,000ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Ni-NTA purified truncated recombinant CK1 expressed in E. Coli strain BL21 (DE3).
Host Species: Mouse
Purification:
Physical State:
CAS NO.: 97-77-8
Product: Disulfiram
Buffer: Ascitic fluid containing 0.03% sodium azide.
Concentration:
Storage Conditions: CK1 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: CK1, CKI-alpha, CK1a, CKIa, HLCDGP1, PRO2975, HEL-S-77p
Accession NO.: P48729
Protein Ino: 31077177
Official Symbol: CSNK1A1
Geneid: 1452
Background: CK1 (also designated Cytokeratin 1 or KRT1 ),with 644-amino acid protein (about 70 kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.
PubMed ID:http://aac.asm.org/content/36/4/801.abstract
