Product Name: CIDE-B Antibody
Species Reactivity: Mouse
Tested Applications: ELISA, WB
Applications: CIDE-B antibody can be used for detection of CIDE-B by Western blot 0.5 μg/mL. An approximately 25 kDa band can be detected.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 25 kDa
Immunogen: CIDE-B antibody was raised against a 16 amino acid peptide near the carboxy terminus of murine CIDE-B.The immunogen is located within the last 50 amino acids of CIDE-B.
Host Species: Rabbit
Purification: CIDE-B Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 638-94-8
Product: Desonide
Buffer: CIDE-B Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
Storage Conditions: CIDE-B antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CIDE-B Antibody: CIDE-B, AI790179, 1110030C18Rik, Cell death activator CIDE-B, Cell death-inducing DFFA-like effector B
Accession NO.: AF041377
Protein Ino: 3114593
Official Symbol: Cideb
Geneid: 12684
Background: CIDE-B Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-B induces apoptosis, which is inhibited by DFF45. CIDE-B is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-B is expressed mainly in liver and at lower levels in spleen, kidney, peripheral blood lymphocytes, and bone marrow.
PubMed ID:http://aac.asm.org/content/36/3/677.abstract
