Product Name: CIDE-A Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, IHC-P, WB
Applications: CIDE-A antibody can be used for detection of CIDE-A by Western blot at 2 μg/mL. An approximately 23 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 23 kDa
Immunogen: CIDE-A antibody was raised against a 18 amino acid peptide near the carboxy terminus of human CIDE-A.The immunogen is located within the last 50 amino acids of CIDE-A.
Host Species: Rabbit
Purification: CIDE-A Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 69655-05-6
Product: Didanosine
Buffer: CIDE-A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
Storage Conditions: CIDE-A antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CIDE-A Antibody: CIDE-A, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A
Accession NO.: AF041378
Protein Ino: 3114595
Official Symbol: CIDEA
Geneid: 1149
Background: CIDE-A Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors. Cell death signals are transduced by DD-, DED-, or CARD-containing molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase DFF40/CAD, which is chaperoned and inhibited by DFF45/ICAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is expressed in many tissues.
PubMed ID:http://aac.asm.org/content/36/3/672.abstract
