Product Name: CEBPB Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: CEBPB antibody can be used for detection of CEBPB by ELISA at 1:1562500. CEBPB antibody can be used for detection of CEBPB by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 36 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CEBPB.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 224177-60-0
Product: Siramesine (hydrochloride)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store CEBPB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CEBPB, LAP, LIP, CRP2, TCF5, IL6DBP, NF-IL6, C/EBP-beta
Accession NO.: NP_005185
Protein Ino: 28872796
Official Symbol: CEBPB
Geneid: 1051
Background: The protein encoded by this intronless gene, CEBPB, is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
PubMed ID:http://aac.asm.org/content/35/10/2091.abstract