Product Name: CDKN1C Antibody
Species Reactivity: Human
Tested Applications: ELISA, IF, WB
Applications: CDKN1C antibody can be used for detection of CDKN1C by Western blot at 1 – 2 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 35 kDa
Immunogen: CDKN1C antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CDKN1C.The immunogen is located within amino acids 40 – 90 of CDKN1C.
Host Species: Rabbit
Purification: CDKN1C Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 36791-04-5
Product: Ribavirin
Buffer: CDKN1C Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CDKN1C antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CDKN1C Antibody: BWS, WBS, p57, BWCR, KIP2, p57Kip2, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57
Accession NO.: NP_000067
Protein Ino: 4557441
Official Symbol: CDKN1C
Geneid: 1028
Background: CDKN1C Antibody: The cyclin-dependent kinase inhibitor 1C (CDKN1C), also known as p57KIP2, is a tight-binding, strong inhibitor of several G1 cyclin/CDK complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndrome, a cancer-predisposing syndrome, suggesting that this gene is a tumor suppressor candidate. CDKN1C is widely expressed during organogenesis with its expression declining after maturity. It is part of the CIP/KIP family of cyclin-dependent inhibitors (CKIs) which also includes CDKN1A and CDKN1B.
PubMed ID:http://aac.asm.org/content/35/9/1811.abstract
