Product Name: CD95 Antibody [EOS9.1]
Species Reactivity: Human
Tested Applications: Flow, Func
Applications:
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Mouse
Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Physical State: liquid
CAS NO.: 522-51-0
Product: Dequalinium (Chloride)
Buffer: Phosphate-buffered aqueous solution, ph7.2.
Concentration: 1 mg/mL
Storage Conditions: The product should be stored undiluted at 4˚C . Do not freeze.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, FAS
Accession NO.:
Protein Ino:
Official Symbol: FAS
Geneid: 355
Background: The EOS9.1 monoclonal antibody specifically reacts with human CD95, a 45 kDA type I membrane molecule. CD95 is a member of the tumor necrosis factor receptor (TNF-R) family and is involved in the mechanisms that lead to cellular apoptosis. It is expressed on fibroblasts, monocytes, lymphocytes, and neutrophils. CD95 induces apoptosis after binding with CD178 or Fas ligand and the EOS9.1 antibody is reported to be used for inducing apoptosis in Fas-positive cells.
PubMed ID:http://aac.asm.org/content/35/6/1191.abstract
