Product Name: CD61 Antibody [25E11.]
Species Reactivity: Human
Tested Applications: Flow, IF, Inhibition
Applications: Flow Cytometry: 0.5-1 ug/million cells in 0.1mlImmunofluorescence: 0.5-1 ug/mlFunctional Activity-Inhibits platelet aggregation (Order SAF formulation)Optimal dilution of the CD61 antibody should be determined by the researcher.
User Note: Optimal dilutions for each application to be determined by the researcher
Predicted Molecular Weight:
Immunogen: Normal blood mononuclear cells activated by mixed lymphocyte reaction were used as the immunogen for the CD61 antibody.
Host Species: Mouse
Purification: PEG precipitation
Physical State: Liquid
CAS NO.: 110267-81-7
Product: Amrubicin
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.2 mg/mL
Storage Conditions: Aliquot and Store at -20C. Avoid freez-thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD61, ITGB3, GP3A
Accession NO.:
Protein Ino:
Official Symbol: ITGB3
Geneid: 3690
Background: Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105kDa reduced and 90kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding.
PubMed ID:http://aac.asm.org/content/35/2/237.abstract