Product Name: CD4 Antibody [9H5A8]
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IHC-P, WB
Applications: CD4 antibody can be used for detection of CD4 by Western blot at 0.5 – 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Mouse monoclonal CD4 antibody was raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.
Host Species: Mouse
Purification: CD4 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
Physical State: Liquid
CAS NO.: 91809-66-4
Product: 5-TAMRA
Buffer: CD4 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CD4 monoclonal antibody can be stored at -20˚C, stable for one year.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: CD4 Antibody [9H5A8] : CD4mut
Accession NO.: NP_000607
Protein Ino: 10835167
Official Symbol: CD4
Geneid: 920
Background: CD4 Monoclonal Antibody: CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
PubMed ID:http://aac.asm.org/content/34/8/1615.abstract
