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Product Name: CD32 Antibody [6C4]
Species Reactivity: Human
Tested Applications: Flow, Func
Applications:
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Mouse
Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Physical State: liquid
CAS NO.: 1313363-54-0
Product: NVP-CGM097
Buffer: Phosphate-buffered aqueous solution, ph7.2.
Concentration: 1 mg/mL
Storage Conditions: The product should be stored undiluted at 4˚C . Do not freeze.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: CD32, FCG2, FcGR, CD32A, CDw32, FCGR2, IGFR2, FCGR2A1, FCGR2A
Accession NO.:
Protein Ino:
Official Symbol: FCGR2A
Geneid: 2212
Background: The 6C4 monoclonal antibody specifically recognizes two isoforms of human CD32, Fc gamma RIIA and Fc gamma RIIB. From alternative mRNA splicing, 6 isoforms of CD32 have been reported. CD32 is a 40 kDA polymorphic transmembrane glycoprotein expressed on monocytes, macrophages, graulocytes, B cells, and platelets. The receptor has low affinity toward IgG and is involved in immunomodulation, phagocytosis, and the inflammation response. The 6C4 antibody in a rosette blocking assay is reported to inhibit Ig binding
PubMed ID:http://aac.asm.org/content/34/7/1318.abstract

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Author: Betaine hydrochloride