Product Name: CD221 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: IGF1R antibody can be used for the detection of IGF1R by Western blot, may also work for IHC and ICC.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 34.9 kDa (calculated)
Immunogen: 214-318
Host Species: Chicken
Purification: Antigen affinity-purified
Physical State: Liquid
CAS NO.: 129909-90-6
Product: Amicarbazone
Buffer: Phosphate-Buffered Saline. No preservatives added.
Concentration: 1 mg/mL
Storage Conditions: CD221 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor, IGF1R
Accession NO.: NP_000866.1
Protein Ino: 4557665
Official Symbol: IGF1R
Geneid: 3480
Background: Insulin-like growth factor 1 receptor. This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates α and β subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
PubMed ID:http://aac.asm.org/content/34/4/632.abstract
