Product Name: CD160 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, IF, WB
Applications: CD160 antibody can be used for detection of CD160 by Western blot at 1 – 2 μg/ml.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 20 kDa Observed: 25kDa
Immunogen: CD160 antibody was raised against a 17 amino acid peptide near the center of human CD160.The immunogen is located within amino acids 50 – 100 of CD160 .
Host Species: Rabbit
Purification: CD160 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1446182-94-0
Product: CUDC-427
Buffer: CD160 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CD160 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CD160 Antibody : NK1, BY55, NK28, CD160 antigen, Natural killer cell receptor BY55
Accession NO.: NP_008984
Protein Ino: 5901910
Official Symbol: CD160
Geneid: 11126
Background: CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1). It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2). CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2,3). Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4).
PubMed ID:http://aac.asm.org/content/34/2/202.abstract
