Product Name: Epo-R (phospho Tyr368) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western Blot: 1:500~1:1000
User Note:
Predicted Molecular Weight: 55 kDa
Immunogen: Epo-R (phospho Tyr368) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine 368 (D-T-Y (p)-L-V) derived from Human Epo-R.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 934541-31-8
Product: TAK-901
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EPO R, EPO-R, epor
Accession NO.: NP_000112.1
Protein Ino: 4503591
Official Symbol: EPOR
Geneid: 2057
Background: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
PubMed ID:http://aac.asm.org/content/40/1/97.abstract
