Product Name: EPAS1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 96 kDa
Immunogen: This EPAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-150 amino acids from the N-terminal region of human EPAS1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 935666-88-9
Product: AZD-1480
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Endothelial PAS domain-containing protein 1, EPAS-1, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, bHLHe73, HIF-1-alpha-like factor, HLF, Hypoxia-inducible factor 2-alpha, HIF-2-alpha, HIF2-alpha, Member of PAS protein 2, PAS domain-containing protein 2, EPAS1, BHLHE73, HIF2A, MOP2, PASD2
Accession NO.: Q99814
Protein Ino: 32470617
Official Symbol: EPAS1
Geneid: 2034
Background: This gene encodes a transcription factor involved in theinduction of genes regulated by oxygen, which is induced as oxygenlevels fall. The encoded protein contains a basic-helix-loop-helixdomain protein dimerization domain as well as a domain found inproteins in signal transduction pathways which respond to oxygenlevels. Mutations in this gene are associated with erythrocytosisfamilial type 4.
PubMed ID:http://aac.asm.org/content/39/11/2588.abstract
