Product Name: EIF2B3 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 50 kDa
Immunogen: This EIF2B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-441 amino acids from the C-terminal region of human EIF2B3.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 945976-76-1
Product: LX-1031
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma, EIF2B3
Accession NO.: Q9NR50
Protein Ino: 18203317
Official Symbol: EIF2B3
Geneid: 8891
Background: The protein encoded by this gene is one of the subunits ofinitiation factor eIF2B, which catalyzes the exchange of eukaryoticinitiation factor 2-bound GDP for GTP. It has also been found tofunction as a cofactor of hepatitis C virus internal ribosome entrysite-mediated translation. Mutations in this gene have beenassociated with leukodystrophy with vanishing white matter.Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.
PubMed ID:http://aac.asm.org/content/39/7/1591.abstract
