Product Name: EGLN2 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: EGLN2 antibody can be used for detection of EGLN2 by ELISA at 1:62500. EGLN2 antibody can be used for detection of EGLN2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 16 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EGLN2.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1245526-82-2
Product: Glucocorticoid receptor agonist
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store EGLN2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EGLN2, EIT6, PHD1, HPH-1, HPH-3, HIFPH1, HIF-PH1
Accession NO.: EAW57007
Protein Ino: 119577411
Official Symbol: EGLN2
Geneid: 112398
Background: The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms.
PubMed ID:http://aac.asm.org/content/39/7/1445.abstract
