Product Name: EFCAB4A Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Applications: EFCAB4A antibody can be used for detection of EFCAB4A by Western blot at 1 – 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: EFCAB4A antibody was raised against a 15 amino acid synthetic peptide near the center of human EFCAB4A.The immunogen is located within amino acids 290 – 340 of EFCAB4A.
Host Species: Rabbit
Purification: EFCAB4A Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1341224-83-6
Product: PF-4136309
Buffer: EFCAB4A Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: EFCAB4A antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EFCAB4A Antibody: CRACR2B, CRACR2B, EF-hand calcium-binding domain-containing protein 4A, Calcium release-activated calcium channel regulator 2B, CRAC channel regulator 2B
Accession NO.: NP_775855
Protein Ino: 150170653
Official Symbol: EFCAB4A
Geneid: 283229
Background: EFCAB4A Antibody: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
PubMed ID:http://aac.asm.org/content/39/5/1154.abstract
