Product Name: EED Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, WB
Applications: EED antibody can be used for detection of EED by Western blot at 2 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 49 kDa Observed: 49 kDa
Immunogen: EED antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human EED.The immunogen is located within amino acids 30 – 80 of EED.
Host Species: Rabbit
Purification: EED Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 159351-69-6
Product: Everolimus
Buffer: EED Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: EED antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: EED Antibody: HEED, WAIT1, Polycomb protein EED, WD protein associating with integrin cytoplasmic tails 1, hEED
Accession NO.: NP_003788
Protein Ino: 24041020
Official Symbol: EED
Geneid: 8726
Background: EED Antibody: The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin β7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.
PubMed ID:http://aac.asm.org/content/39/5/1097.abstract
