Product Name: DRAK2 Antibody
Species Reactivity: Human
Tested Applications: ELISA, ICC, WB
Applications: DRAK2 antibody can be used for detection of DRAK2 by Western blot 0.5 μg/mL. An approximately 45 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 10 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: DRAK2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human DRAK2.The immunogen is located within the last 50 amino acids of DRAK2.
Host Species: Rabbit
Purification: DRAK2 Antibody is Ion exchange chromatography purified.
Physical State: Liquid
CAS NO.: 71751-41-2
Product: Avermectin B1
Buffer: DRAK2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
Storage Conditions: DRAK2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: DRAK2 Antibody: DRAK2, DRAK2, DAP kinase-related apoptosis-inducing protein kinase 2
Accession NO.: AB011421
Protein Ino: 3834355
Official Symbol: STK17B
Geneid: 9262
Background: DRAK2 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase-related apoptosis-inducing protein kinases). DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
PubMed ID:http://aac.asm.org/content/38/12/2905.abstract
