Product Name: DAZ3 Antibody
Species Reactivity: Human
Tested Applications: IHC-P, WB
Applications: For WB starting dilution is: 1:1000For IHC-P starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 55 kDa
Immunogen: This DAZ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human DAZ3.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 956136-95-1
Product: LCQ-908
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Deleted in azoospermia protein 3, DAZ3
Accession NO.: Q9NR90
Protein Ino: 44887842
Official Symbol: DAZ3
Geneid: 57054
Background: This gene is a member of the DAZ gene family and is acandidate for the human Y-chromosomal azoospermia factor (AZF). Itsexpression is restricted to premeiotic germ cells, particularly inspermatogonia. It encodes an RNA-binding protein that is importantfor spermatogenesis. Four copies of this gene are found onchromosome Y within palindromic duplications; one pair of genes ispart of the P2 palindrome and the second pair is part of the P1palindrome. Each gene contains a 2.4 kb repeat including a 72-bpexon, called the DAZ repeat; the number of DAZ repeats is variableand there are several variations in the sequence of the DAZ repeat.Each copy of the gene also contains a 10.8 kb region that may beamplified; this region includes five exons that encode an RNArecognition motif (RRM) domain. This gene contains one copy of the10.8 kb repeat.
PubMed ID:http://aac.asm.org/content/38/3/428.abstract
