Product Name: Cytochrome C Antibody [CYC5420]
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western blot: 2-4 ug/mlProvided assay concentrations are suggestions only, antibody titration may be required for optimal results.
User Note: Optimal dilutions for each application to be determined by the researcher
Predicted Molecular Weight:
Immunogen: Recombinant human Cytochrome C was used as the immunogen for this antibody.
Host Species: Mouse
Purification: Protein G purified antibody
Physical State: Liquid
CAS NO.: 23261-20-3
Product: VAL-083
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.5 mg/mL
Storage Conditions: Aliquot and Store at -20C. Avoid freez-thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: CYCS, CYC, HCS, THC4, Cytochrome c, Cytochrome c, somatic
Accession NO.:
Protein Ino:
Official Symbol: CYCS
Geneid: 54205
Background: Cytochrome C (CYC) is a Class I member of the Cytochrome C family, found in the mitochondria of cells, and bacteria. In the mitochondria, it accepts electrons from CYB and transfers them to the cytochrome oxidase complex. Apoptosis is a physiological process involved in development, homeostasis and host defense. In mammals, Cytochrome C is an initiator of apoptosis. When released from mitochondria, it binds to Apaf-1 and ATP to form the apoptosome. This complex cleaves and activates initiator caspases-9, which in turn activates effector caspase-3, beginning the caspase cascade of the apoptotic pathway.
PubMed ID:http://aac.asm.org/content/37/12/2540.abstract
