Product Name: Cyclin D1 (phospho Thr286) Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB
Applications: Western Blot: 1:500~1:1000
User Note:
Predicted Molecular Weight: 33 kDa
Immunogen: Cyclin D1 (phospho Thr286) antibody was raised against a peptide sequence around phosphorylation site of threonine 286 (A-C-T (p)-P-T) derived from Human Cyclin D1.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 6559-91-7
Product: 4-Demethylepipodophyllotoxin
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: BCL-1 , oncogene, CYL-1, PRAD1, PRAD1
Accession NO.: NP_444284.1
Protein Ino: 116152
Official Symbol: CCND1
Geneid: 595
Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-48-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
PubMed ID:http://aac.asm.org/content/37/9/2033.abstract
