Product Name: CYBA Antibody
Species Reactivity: Human
Tested Applications: IF, WB
Applications: For WB starting dilution is: 1:1000For IF starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 21 kDa
Immunogen: This CYBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the C-terminal region of human CYBA.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1240299-33-5
Product: AZD3514
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cytochrome b-245 light chain, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox, CYBA
Accession NO.: P13498
Protein Ino: 311033459
Official Symbol: CYBA
Geneid: 1535
Background: Cytochrome b is comprised of a light chain (alpha) and aheavy chain (beta). This gene encodes the light, alpha subunitwhich has been proposed as a primary component of the microbicidaloxidase system of phagocytes. Mutations in this gene are associatedwith autosomal recessive chronic granulomatous disease (CGD), thatis characterized by the failure of activated phagocytes to generatesuperoxide, which is important for the microbicidal activity ofthese cells.
PubMed ID:http://aac.asm.org/content/37/9/1971.abstract
