Product Name: CX3CR1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, Flow, IF, IHC-P, WB
Applications: CX3CR1 antibody can be used for detection of CX3CR1 by Western blot at 0.5 – 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2 μg/mL. For immunofluorescence start at 10 μg/mL. Flow cytometry at 0.1 μg/ml.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 50 kDa Observed: 52 kDa
Immunogen: CX3CR1 antibody was raised against a 20 amino acid peptide near the amino terminus of human CX3CR1.The immunogen is located within the first 50 amino acids of CX3CR1.
Host Species: Rabbit
Purification: CX3CR1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 168555-66-6
Product: Fosbretabulin (disodium)
Buffer: CX3CR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CX3CR1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CX3CR1 Antibody: V28, CCRL1, GPR13, CMKDR1, GPRV28, CMKBRL1, CX3C chemokine receptor 1, Beta chemokine receptor-like 1, C-X3-C CKR-1
Accession NO.: NP_001328
Protein Ino: 4503171
Official Symbol: CX3CR1
Geneid: 1524
Background: CX3CR1 Antibody: CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, murine, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
PubMed ID:http://aac.asm.org/content/37/8/1723.abstract