Product Name: CTRP1 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, WB
Applications: CTRP1 antibody can be used for the detection of CTRP1 by Western blot at 1 and 2 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: CTRP1 (IN) antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP1.The immunogen is located within amino acids 80 – 130 of CTRP1.
Host Species: Rabbit
Purification: CTRP1 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 58-60-6
Product: Puromycin aminonucleoside
Buffer: CTRP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CTRP1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CTRP1 Antibody: GIP, CTRP1, ZSIG37, UNQ310/PRO353, Complement C1q tumor necrosis factor-related protein 1, G protein-coupled receptor-interacting protein, GIP
Accession NO.: NP_940995
Protein Ino: 38372917
Official Symbol: C1QTNF1
Geneid: 114897
Background: CTRP1 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.
PubMed ID:http://aac.asm.org/content/37/7/1436.abstract
