Product Name: CTHRC1 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: CTHRC1 antibody can be used for detection of CTHRC1 by Western blot at 1 – 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 27 kDa Observed: 27 kDa
Immunogen: CTHRC1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CTHRC1.The immunogen is located within the first 50 amino acids of CTHRC1.
Host Species: Rabbit
Purification: CTHRC1 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 139755-83-2
Product: Sildenafil
Buffer: CTHRC1 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CTHRC1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Collagen triple helix repeat-containing protein 1
Accession NO.: NP_612464
Protein Ino: 19923989
Official Symbol: CTHRC1
Geneid: 115908
Background: The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration (1). CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells (2). CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer (3). Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma (4).
PubMed ID:http://aac.asm.org/content/37/6/1318.abstract
