Product Name: Cryopyrin Antibody
Species Reactivity: Human
Tested Applications: ELISA, Flow
Applications: ELISA: antibody detection limit dilution 1:32000. Western Blot: No signal obtained yet but low background observed in A431 lysates at up to 1μg/ml. We would appreciate any feedback from people in the field – have any results been reported with other antibodies/lysates? Flow cytometry: Customer finds it to work well in FC on human monocytes.
User Note:
Predicted Molecular Weight:
Immunogen: Cryopyrin antibody was raised against a 13 amino acid synthetic peptide near the C-Terminus of Cryopyrin.
Host Species: Goat
Purification: Cryopyrin antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Physical State: Liquid
CAS NO.: 852391-15-2
Product: Necrostatin 2 (racemate)
Buffer: Cryopyrin antibody is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
Concentration: 500 ug/mL
Storage Conditions: Aliquot and store at -20˚C. Minimize freezing and thawing.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CIAS1, FCU, MWS, FCAS, NALP3, C1orf7, PYPAF1, AII/AVP, AGTAVPRL, CRYOPYRIN, cold autoinflammatory syndrome 1, cryopyrin, Muckle-Wells syndrome, chromosome 1 open reading frame 7, PYRIN-containing APAF1-like protein 1, neuronal apoptosis inhibitor protein 3, angiotensin/vasopressin receptor AII/AVP-like, CIAS1
Accession NO.: NP_004886
Protein Ino: 34878693
Official Symbol: NLRP3
Geneid: 114548
Background:
PubMed ID:http://aac.asm.org/content/37/4/851.abstract