Product Name: CRFR1 Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000For FACS starting dilution is: 1:10~50
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 51 kDa
Immunogen: This CRFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-119 amino acids from human CRFR1.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 1239908-20-3
Product: MLN9708
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.26 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Corticotropin-releasing factor receptor 1, CRF-R-1, CRF-R1, CRFR-1, Corticotropin-releasing hormone receptor 1, CRH-R-1, CRH-R1, CRHR1, CRFR, CRFR1, CRHR
Accession NO.: P34998
Protein Ino: 461836
Official Symbol: CRHR1
Geneid: 1394
Background: This gene encodes a G-protein coupled receptor that bindsneuropeptides of the corticotropin releasing hormone family thatare major regulators of the hypothalamic-pituitary-adrenal pathway.The encoded protein is essential for the activation of signaltransduction pathways that regulate diverse physiological processesincluding stress, reproduction, immune response and obesity.Alternative splicing results in multiple transcript variants.
PubMed ID:http://aac.asm.org/content/37/3/532.abstract
