Product Name: CREB3 Antibody
Species Reactivity: Dog, Human
Tested Applications: ELISA, WB
Applications: CREB3 antibody can be used for detection of CREB3 by ELISA at 1:312500. CREB3 antibody can be used for detection of CREB3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 41 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREB3.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1379573-92-8
Product: CBB1007
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store CREB3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CREB3, LZIP, LUMAN
Accession NO.: NP_006359
Protein Ino: 22219462
Official Symbol: CREB3
Geneid: 10488
Background: CREB3 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined.
PubMed ID:http://aac.asm.org/content/37/3/414.abstract
