Product Name: COX3 Antibody
Species Reactivity: Human
Tested Applications: ELISA, WB
Applications: COX3 antibody can be used for detection of COX3 by ELISA at 1:1562500. COX3 antibody can be used for detection of COX3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 29 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COX3.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 50924-49-7
Product: Mizoribine
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store COX3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: COX3, MTCO3, COIII, COX3
Accession NO.: NP_536849
Protein Ino: 17981859
Official Symbol: COX3
Geneid: 4514
Background: COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency). Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
PubMed ID:http://aac.asm.org/content/36/12/2816.abstract
