Product Name: COCH Antibody
Species Reactivity: Human
Tested Applications: WB
Applications: For WB starting dilution is: 1:1000
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 59 kDa
Immunogen: This COCH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 492-520 amino acids from the C-terminal region of human COCH.
Host Species: Rabbit
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Physical State: Liquid
CAS NO.: 57-83-0
Product: Progesterone
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: 0.5 mg/ml
Storage Conditions: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cochlin, COCH-5B2, COCH, COCH5B2
Accession NO.: O43405
Protein Ino:
Official Symbol: COCH
Geneid: 1690
Background: The protein encoded by this gene is highly conserved inhuman, mouse, and chicken, showing 94% and 79% amino acid identityof human to mouse and chicken sequences, respectively.Hybridization to this gene was detected in spindle-shaped cellslocated along nerve fibers between the auditory ganglion andsensory epithelium. These cells accompany neurites at the habenulaperforata, the opening through which neurites extend to innervatehair cells. This and the pattern of expression of this gene inchicken inner ear paralleled the histologic findings of acidophilicdeposits, consistent with mucopolysaccharide ground substance, intemporal bones from DFNA9 (autosomal dominant nonsyndromicsensorineural deafness 9) patients. Mutations that cause DFNA9 havebeen reported in this gene. Alternative splicing results inmultiple transcript variants encoding the same protein. Additionalsplice variants encoding distinct isoforms have been described buttheir biological validities have not been demonstrated. [providedby RefSeq].
PubMed ID:http://aac.asm.org/content/36/9/2057.abstract
