Product Name: CMKLR1 Antibody [BZ332]
Species Reactivity: Human
Tested Applications: Flow, IHC
Applications: CMKLR1 antibody can be used in Western Blot, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: CMKLR1 monoclonal antibody was raised against a peptide near the N-Terminus of CMKLR1 (Human).
Host Species: Rat
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 229005-80-5
Product: TAK-779
Buffer: PBS, pH 7.4, 0.09% sodium azide.
Concentration:
Storage Conditions: Store CMKLR1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Monoclonal
Conjugate: Unconjugated
Alternate Names: CMKLR1, Chemokine receptor-like 1, DEZ, CHEMERINR, Resolvin E1 receptor, RVER1, Chemokine-like receptor 1, ChemR23, G-protein coupled receptor DEZ
Accession NO.: Q99788
Protein Ino: 17380487
Official Symbol: CMKLR1
Geneid: 1240
Background: Recognizes human serpentine chemokine-like receptor 1 (CMKLR1), a novel chemoattractant receptor, which is also referred to Chem23 or DEZ. CMKLR1 is expressed on plasmacytoid dendritic cells (pDC) in blood but is not expressed on myeloid dendritic cells, lymphocytes, monocytes or granulocytes. Studies show that CMKLR1 is also expressed on dendritic cells, which have been generated in vitro from monocytes. The sole ligand for CMKLR1 is chemerin, a chemoattractant that exists at the mRNA level in a wide range of tissues, and as an inactive proform in serum and plasma. Studies suggest that chemerin, in plasma, is converted into a potent pDC attractant following blood coagulation and may be a process by which pDCs are recruited to sites of bleeding and tissue damage
PubMed ID:http://aac.asm.org/content/36/8/1715.abstract
