Product Name: CLCNKB Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC, WB
Applications: CLCNKB antibody can be used for detection of CLCNKB by ELISA at 1:312500. CLCNKB antibody can be used for detection of CLCNKB by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 50 kDa, 75 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLCNKB.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 147098-20-2
Product: Rosuvastatin (Calcium)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store CLCNKB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CLCNKB, RP11-5P18.8, CLCKB, ClC-K2, MGC24087, hClC-Kb, ClC-Kb
Accession NO.: AAH20873
Protein Ino: 18088621
Official Symbol: CLCNKB
Geneid: 1188
Background: Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
PubMed ID:http://aac.asm.org/content/36/5/1057.abstract