Product Name: CHD4 Antibody
Species Reactivity: Human
Tested Applications: ELISA, IHC
Applications: CHD4 antibody can be used in ELISA starting at 1:2000 – 1:10000, Western Blot starting at 1:500 – 1:1000, immunohistochemistry starting at 1:500, and immunoprecipitation
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen:
Host Species: Rabbit
Purification: Protein G Column
Physical State: Liquid
CAS NO.: 57381-26-7
Product: Irsogladine
Buffer: PBS, 0.09% sodium azide.
Concentration:
Storage Conditions: Antibody should be stored long term (months) at -20 ˚C and short term (weeks) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CHD4, ATP-dependent helicase CHD4, CHD-4, Mi-2b, Mi2-BETA
Accession NO.: Q14839
Protein Ino: 311033360
Official Symbol: CHD4
Geneid: 1108
Background: The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. Patients with dermatomyositis develop antibodies against the nuclear antigen chromodomain helicase DNA binding protein 4. The protein exists in a complex containing histone deacetylase and nucleosome remodeling activities, suggesting a role for chromatin reorganization in cancer metastasis.
PubMed ID:http://aac.asm.org/content/35/12/2655.abstract