Product Name: CENTG1 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, IF, IHC, WB
Applications: CENTG1 antibody can be used in Western Blot, and immunohistochemistry starting at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: Amino acids 1-836 of human AGAP2 protein.
Host Species: Rabbit
Purification: Protein A Column
Physical State: Liquid
CAS NO.: 611-75-6
Product: Bromhexine (hydrochloride)
Buffer: PBS, pH 7.2, 0.01% sodium azide.
Concentration:
Storage Conditions: Store CENTG1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: AGAP2, AGAP-2, Centaurin, gamma 1, Cnt-g1, Centaurin-gamma-1, KIAA0167, GGAP2, PIKE, CENTG1
Accession NO.: Q99490
Protein Ino: 97535883
Official Symbol: AGAP2
Geneid: 116986
Background: AGAP2 (also known as centaurin-gamma1, ARF-GAP with GTP-binding protein-like, ankyrin repeat and pleckstrin homology domains 2, Phosphatidyl-inositol-3-kinase enhancer, PIKE, GTP-binding and GTPase activating protein 2 and GGAP2) is a GTPase activating protein that inactivates Arf. The expression of AGAP2 is amplified in human glioblastoma cells. AGAP2 protein binds to and activates the protein kinase Akt and prevents apoptosis of cancer cells. AGAP2 also increases motility and invasive activity of cancer cells. AGAP2 may serve as a diagnostic and therapeutic target of human cancer.
PubMed ID:http://aac.asm.org/content/35/11/2275.abstract
