Product Name: CCDC134 Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, IHC-P, WB
Applications: CCDC134 antibody can be used for detection of CCDC134 by Western blot at 1 – 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: CCDC134 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CCDC134.The immunogen is located within the first 50 amino acids of CCDC134.
Host Species: Rabbit
Purification: CCDC134 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 36062-07-4
Product: Octahydrocurcumin
Buffer: CCDC134 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CCDC134 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CCDC134 Antibody: dJ821D11.3, Coiled-coil domain-containing protein 134
Accession NO.: NP_079097
Protein Ino: 13376216
Official Symbol: CCDC134
Geneid: 79879
Background: CCDC134 Antibody: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
PubMed ID:http://aac.asm.org/content/43/7/1616.abstract
