Product Name: CBX2 Antibody
Species Reactivity: Human, Mouse
Tested Applications: ELISA, WB
Applications: CBX2 antibody can be used for detection of CBX2 by ELISA at 1:1562500. CBX2 antibody can be used for detection of CBX2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 – 100,000.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: 56 kDa
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CBX2.
Host Species: Rabbit
Purification: Antibody is purified by peptide affinity chromatography method.
Physical State: Lyophilized
CAS NO.: 1309357-15-0
Product: CX-4945 (sodium salt)
Buffer: Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Concentration: 1 mg/ml
Storage Conditions: For short periods of storage (days) store at 4˚C. For longer periods of storage, store CBX2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CBX2, CDCA6, M33, MGC10561, SRXY5
Accession NO.: NP_005180
Protein Ino: 61743963
Official Symbol: CBX2
Geneid: 84733
Background: CBX2 Contains 1 A.T hook DNA-binding domain and 1 chromo domain. CBX2 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.
PubMed ID:http://aac.asm.org/content/43/7/1788.abstract
