Product Name: CASKIN2 Antibody
Species Reactivity: Human
Tested Applications: ELISA, ICC, IF, WB
Applications: CASKIN2 antibody can be used for detection of EPAC1 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 5 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 123, 132 kDa Observed: 120 kDa
Immunogen: CASKIN2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human CASKIN2.The immunogen is located within amino acids 380 – 430 of CASKIN2.
Host Species: Rabbit
Purification: CASKIN2 Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 953769-46-5
Product: BLZ945
Buffer: CASKIN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CASKIN2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CASKIN2 Antibody: ANKS5B, KIAA1139, Caskin-2, CASK-interacting protein 2
Accession NO.: NP_065804
Protein Ino: 217416347
Official Symbol: CASKIN2
Geneid: 57513
Background: CASKIN2 Antibody: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting protein ) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN2 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. It is expressed ubiquitously with highest levels present in fetal and adult liver tissue.
PubMed ID:http://aac.asm.org/content/43/4/972.abstract
