Product Name: CASK Antibody
Species Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, IF, WB
Applications: CASK antibody can be used for detection of CASK by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight:
Immunogen: CASK antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CASK.The immunogen is located within amino acids 760 – 810 of CASK.
Host Species: Rabbit
Purification: CASK Antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 393105-53-8
Product: Tiplaxtinin
Buffer: CASK Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CASK antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: CASK Antibody: CMG, FGS4, LIN2, TNRC8, CAGH39, CAMGUK, MICPCH, MRXSNA, Peripheral plasma membrane protein CASK, Protein lin-2 homolog, hCASK
Accession NO.: NP_003679
Protein Ino: 186972120
Official Symbol: CASK
Geneid: 8573
Background: CASK Antibody: CASK (Calcium/calmodulin-dependent serine protein kinase), a conserved multi-domain scaffolding protein, belongs to a MAGUK (membrane-associated guanylate kinase homologs) subfamily and is involved in cell junction organization, tumor suppression and signaling. It is characterized by a novel domain structure that consists of a calcium/calmodulin-dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is ubiquitously expressed and significantly greater in brain where it is thought to be involved in signaling at neuronal synapses. CASK interacts with CASKINs and defects in CASK are the cause of mental retardation X-linked CASK-related.
PubMed ID:http://aac.asm.org/content/43/4/876.abstract
