Product Name: CADM3 Antibody
Species Reactivity: Mouse, Rat
Tested Applications: IF, IHC-P, WB
Applications: CADM3 antibody can be used for detection of CADM3 by Western blot at 1 – 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
User Note: Optimal dilutions for each application to be determined by the researcher.
Predicted Molecular Weight: Predicted: 44, 48 kDa Observed: 50 kDa
Immunogen: CADM3 antibody was raised against a 16 amino acid peptide near the center of human CADM3.The immunogen is located within amino acids 220 – 270 of CADM3.
Host Species: Rabbit
Purification: CADM3 antibody is affinity chromatography purified via peptide column.
Physical State: Liquid
CAS NO.: 1215641-01-2
Product: Prochlorperazine D8
Buffer: CADM3 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Conditions: CADM3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: Cell adhesion molecule 3, BIgR, NECL1, Necl-1, TSLL1, IGSF4B, synCAM3
Accession NO.: NP_067012
Protein Ino: 11056046
Official Symbol: CADM3
Geneid: 57863
Background: Cell adhesion molecule 3 (CADM3) is a member of a family of immunoglobulin-like, calcium-independent cell-cell adhesion molecules (1,2). CADM3 localizes to non-junctional contact sites of presynaptic nerve terminals, axons and glia cell processes and is thought to play an important role in the formation of synapses, axon bundles and myelinated axons (3). Recently, CADM3 has been shown to suppress the growth and tumorigenic ability of colon cancer cells, indicating that it can act as a tumor suppressor (4).
PubMed ID:http://aac.asm.org/content/43/1/141.abstract
