Product Name: CAD (phospho Thr456) Antibody
Species Reactivity: Human, Mouse
Tested Applications: IHC
Applications:
User Note:
Predicted Molecular Weight: 242 kDa
Immunogen: CAD (phospho Thr456) antibody was raised against a peptide sequence around phosphorylation site of threonine 456 (P-I-T (p)-P-H) derived from Human CAD.
Host Species: Rabbit
Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Physical State: Liquid
CAS NO.: 949095-98-1
Product: Duloxetine metabolite Para-Naphthol Duloxetine
Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration: 1 mg/mL
Storage Conditions: Store antibody at -20˚C for up to one year.
Clonality: Polyclonal
Conjugate: Unconjugated
Alternate Names: PYR1, CAD protein, EC 2.1.3.2, EC 3.5.2.3
Accession NO.: NP_004332.2
Protein Ino: 50403731
Official Symbol: CAD
Geneid: 790
Background: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
PubMed ID:http://aac.asm.org/content/43/1/73.abstract
